Glomerular Diseases

Glomerular Diseases

Many diseases affect kidney function by damaging the glomeruli, the tiny units within the kidney where blood is cleaned. Glomerular diseases comprise many conditions with a variety of genetic and environmental causes, but they fall into two major categories.

Glomerular diseases damage the glomeruli, allowing protein and sometimes red blood cells drip into the urine. Sometimes a glomerular disease also hinders the clearance of waste products by the kidney, so they begin to build up in the blood. Furthermore, loss of blood proteins like albumin in the urine can result in a fall in their level in the bloodstream. In normal blood, albumin acts like a sponge, drawing extra fluid from the body into the bloodstream, where it resides until the kidneys remove it. But when albumin leaks into the urine, the blood loses its capacity to absorb extra fluid from the body. Fluid can accumulate outside the cardiovascular system in the face, hands, feet, or ankles and cause swelling.

Glomerular disease sometimes develops rapidly after an infection in other parts of the body.

  • Glomerulonephritis
  • Acute post-streptococcal Glomerulonephritis
  • Bacterial Endocarditis
  • Glomerulosclerosis
  • Diabetic Nephropathy
  • Focal Segmental Glomerulosclerosis
  • Membranous Nephropathy

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