Ebola and Zika viruses represent major global health threats due to their high transmission potential and severe complications. Ebola causes hemorrhagic fever with high mortality rates, primarily spreading through bodily fluids. Zika, transmitted by mosquitoes, is linked to neurological damage and congenital birth defects. Ongoing research focuses on developing vaccines, antiviral therapies, and effective outbreak response strategies. Surveillance, vector control, and community awareness remain critical to reducing transmission. Strengthening global healthcare systems enhances preparedness for future outbreaks of these and other emerging viruses.