The One Health approach recognizes the interconnectedness of human, animal, and environmental health in addressing complex global health challenges. Increasing urbanization, climate change, antimicrobial resistance, zoonotic diseases, food security, and ecosystem changes have emphasized the importance of collaborative, multidisciplinary approaches to healthcare. One Health promotes integrated surveillance, disease prevention, emergency preparedness, and sustainable health policies involving healthcare professionals, veterinarians, environmental scientists, public health experts, and policymakers. Strengthening collaboration across these sectors is essential for preventing emerging infectious diseases, improving health security, and achieving sustainable development goals. This session welcomes innovative research, policy initiatives, case studies, and practical strategies that advance One Health principles and improve global health resilience.