Melanoma
Melanoma
Melanoma the most aggressive skin cancer, originates from genetic mutations in melanocytes—pigment-producing cells in the skin, eye, ear, and leptomeninges. UV radiation, particularly impactful for individuals with less melanin, is a primary cause. Suspicious skin lesions are biopsied for potential malignancy. In the United States, melanoma is rare, affecting 22.1 per 100,000, but it's lethal, causing 75% of skin cancer deaths despite comprising only 4% of cases. The mnemonic "ABCDEF" captures melanoma's early signs: Asymmetry, Borders (uneven), Color (varied), Diameter (>6 mm), Evolving appearance over time. Early detection is crucial, as melanoma responds well to treatment when detected early.
- Metastatic Melanoma
- Malignant Melanoma
- Combat Melanoma
- Scleroderma
- Biomarkers