Obesity and Metabolism for Diabetes
Obesity and Metabolism for Diabetes
Obesity plays a significant role in the development and progression of type 2 diabetes, as excess adiposity contributes to insulin resistance and dysregulated glucose metabolism. Adipose tissue secretes adipokines and inflammatory cytokines that disrupt insulin signaling pathways and promote systemic inflammation, exacerbating insulin resistance. Moreover, obesity is often accompanied by metabolic abnormalities such as dyslipidemia and hypertension, further increasing the risk of diabetes and cardiovascular complications. Understanding the intricate relationship between obesity and metabolism is essential for developing effective interventions to prevent and manage diabetes. Lifestyle modifications, including weight loss through diet and exercise, remain cornerstone strategies for addressing obesity-related diabetes. Additionally, pharmacological agents targeting obesity-associated pathways may offer adjunctive therapies for improving metabolic health in individuals with diabetes. The Obesity and Metabolism for Diabetes session at the Diabetes 2024 summit will explore the latest research and interventions aimed at addressing obesity-related metabolic dysfunction in the context of diabetes.
Keywords: obesity, metabolism, type 2 diabetes, insulin resistance, dysregulated glucose metabolism, adipokines, inflammatory cytokines, dyslipidemia, hypertension, lifestyle modifications, pharmacological interventions, metabolic dysfunction.