Insulin Action/Molecular Metabolism
Insulin Action/Molecular Metabolism
Insulin action and molecular metabolism are fundamental aspects of diabetes pathophysiology, offering valuable insights into disease mechanisms and potential therapeutic targets. Insulin, a key hormone produced by pancreatic beta cells, plays a central role in regulating glucose metabolism in the body. Upon binding to its receptor, insulin triggers a cascade of molecular events that facilitate glucose uptake into cells, promote glycogen synthesis in the liver and muscles, and inhibit gluconeogenesis. Disruptions in insulin signaling pathways can lead to insulin resistance, a hallmark of type 2 diabetes, characterized by impaired glucose uptake and dysregulated lipid metabolism.
Keywords: insulin action, molecular metabolism, glucose metabolism, insulin resistance, signaling pathways, metabolic homeostasis, therapeutic targets, personalized approaches, diabetes prevention.