Shanghai JiaoTong University, China
We have collaborated with experts from relevant branches of the CMA, as well as experts from multiple disciplines, based on the foundation and clinical research progress of Wilson's disease at home and abroad 2024.
We have been sponsored by MDS in the field of Rare Movement Disorders program, DWEP) .
For a rare disease Wilson’s disease (WD), the data is not comprehensive. It is possible to fully cover or solve all the problems in the diagnosis and treatment of WD. We hope that further international/domestic multicenter RCT research can be carried out to gradually improve to perfection.
1. Any age, especially adolescents and young patients, who experience unexplained liver dysfunction or neurological and psychiatric symptoms, should consider screening for WD
2. Suspected individuals with WD should undergo K-F ring examination, and it is recommended that experienced ophthalmologists use slit lamp examination.6. Brain MRI examination can serve as a means for evaluating the condition of WD patients with neurological disorders and monitoring treatment efficacy (1A), especially QSM technique, however Brain MRI T7 is much sensitve but not easy to acess to it and not reconmmend it.
WD is a genetic metabolic disease that can be cured with drugs, and its long-term prognosis depends on the timing of early treatment, and there is currently no suitable treatment drug for all WD patients. Also the alternative treatments of splenectomy, liver transplantation have the positive action, and the genetic & cell tretments are on the way.
Xiaoping Wang is affiliated with Shanghai Jiao Tong University School of Medicine, China, and contributes actively to research and academic development in the medical sciences.