This study was carried out in two phases; the first synthesis and characterization of Silver Tranexamate, for this purpose aqueous solutions of tranexamic acid and sodium hydroxide 0.005 mol each were mixed, stirred for 30 minutes, then an aqueous solution of silver nitrate 0.005 mol was added little by little; after 1 hour of stirring in a hermetically sealed container, a white solution was obtained; it was filtered and left in an oven at 30 ° C for 1 hour. A 65% reaction yield was obtained. For the characterization the following were carried out: IR Spectroscopy, Nuclear Magnetic Resonance, Raman, Elemental Analysis, Thermogravimetric Analysis. In the second phase, o/w creams were prepared based on the synthesized complex at concentrations of 0.25%, 0.5%, 1% and 2%. The Kirby Bauer method was used to determine the antibacterial effect of the cream in question. Statistical tests such as Levene's, Annova's, and Tukey's were used to identify statistical differences between the different concentrations. The complex was synthesized, and it was determined that the 2% o/w cream had the best antibacterial effect, but less so than silver sulfadiazine, with a 95% confidence level and a 0.05% error rate. Future research could be conducted with other bacteria present in burn wounds.

Msc. Q.F. Guillermo José Gallardo Vásquez is a graduate of the National University of Trujillo - Peru, with a Master's degree in Preparation and Development of Individualized Medications from the CEU San Pablo University - Spain, currently pursuing a Master's degree in Chemistry at the El Milagro State University - Ecuador and is General Manager of the company Farmacia Magistral JPG SKIN.