Drug Development or exploration of new lead compounds is always remain a fundamental field in health sciences. Drug resistance, environmental changes, emerging diseases and previously untreatable diseases with lesser side effects and better efficacy are main causes for the researchers/pharmacists to discover new bioactive compounds for drug development.

Electrified and thrilled by the above mentioned facts, we were interested to develop some novel bioactive heterocycles for drug development. In literature, Thiadiazines heterocycles have good biological insights but with lesser derivatives development due to its tricky nature. Therefore, we successfully synthesized and reported several potent activities on Thiadiazines recently (see references 1-6). Our newly developed Thiadiazines showed several biological activities including potent anti-leishmanial, anti- inflammatory, anti-cancer, urease inhibition, analgesic, antimicrobial etc and their primarily model testing as prodrug candidate has been also positively explored .

Mr. Hashim has worked for Drug discovery as Postdoctoral fellow at BOKU University, Vienna, Austria-2023. In addition to this, Mr. Hashim did his PhD/Post doctorate on Bio-active Heterocycles from Karl Franzens University of Graz, Austria under the supervision of Prof. C. Oliver Kappe. Further to this, he has also more than 10 years research experience as an Assistant Professor/Co-PI at University of Lakki Marwat/ University of Karachi, NEDUET, Karachi, and Fauji Fertilizer Ltd. He has already developed some novel heterocycles (Thiadiazines); dihydropyrimidines and Natural Products Derived Crown Ethers. Alongside 25 papers in reputed journals; 04 patents have been already submitted on his recent findings