Ophthalmogenetics and Gene Therapy
Ophthalmogenetics and Gene Therapy
The complex process of normal eye development during the first trimester of pregnancy involves multiple genes. Mutations in these genes can lead to serious eye conditions. Ophthalmic genetics is a rapidly growing field globally, addressing the impact of ethnic diversity and consanguinity on the prevalence of genetic disorders. Inherited retinal disease (IRD) is a leading cause of working-age blindness. Advances in molecular genetics, including focused gene panels and next-generation sequencing, have expedited molecular diagnosis. Enhanced ocular imaging and visual function tests provide insights into natural history, crucial for evaluating potential IRD treatments in clinical trials.
- Molecular Biology
- Ophthalmic Genetics
- Retinal Imaging
- Stem Cells