Gynecology 2027

Background

Adipose tissue has evolved from being considered a passive energy reservoir to one of the most accessible sources of regenerative cells, extracellular matrix, and potent paracrine mediators. In reproductive medicine, this has created a compelling question: can adipose tissue be transformed from a readily available biological resource into a clinically meaningful regenerative tool?

Objectives

To provide a clinically oriented framework for understanding and translating adipose-derived regenerative approaches into gynaecological practice, with particular emphasis on MFAT, SVF and AD-MSCs.

Key Discussion

The presentation will address:

1. What is actually inside adipose tissue? Fat architecture— cellular/ stromal, extracellular matrix

2. MFAT versus SVF — biology, processing and clinical differences

3. Fat harvesting

4. SVF processing

5. Potential applications in reproductive and gynaecological medicine, including ovarian and endometrial regenerative research

6. Current clinical evidence, limitations and unanswered questions

7. Patient selection, safety, standardisation and ethical/regulatory considerations

Conclusion

Adipose tissue is increasingly recognised as a biologically active reservoir of regenerative cells and signalling molecules rather than simply an energy-storage tissue. However, translating biological promise into reproducible clinical benefit requires appropriate patient selection, standardised processing, rigorous safety assessment and high-quality clinical evidence. Understanding what we are actually delivering—MFAT, SVF or cultured cells—is fundamental to responsible regenerative gynaecology.

Proposed Take-Home Message

The future of adipose-based regenerative gynaecology lies not simply in “using fat”, but in understanding its cellular composition, biological signals, processing and evidence.

Dr. Alnkrita Bansal is an Obstetrician and Gynaecologist, Regenerative Gynaecologist, and healthcare leader based in Rudrapur, Uttarakhand, India. She serves as the Managing Director of HB Speciality Hospital and Director of Revita Life Sciences Pvt. Ltd. Her clinical interests focus on regenerative medicine and reproductive health, particularly ovarian rejuvenation, Primary Ovarian Insufficiency, and infertility. Her areas of expertise include adipose-derived mesenchymal stem cells, stromal vascular fraction (SVF), MFAT, intra-ovarian PRP, exosomes, and other regenerative therapies. Dr. Bansal holds an M.S. in Obstetrics & Gynaecology from GITAM Medical College, a PDCC in IVF from SRMS IMS, Bareilly, and an MBBS from SRMS Institute of Medical Sciences. She has clinical experience at AIIMS Rishikesh, SRMS IMS, and ESIC Hospital, Rudrapur. She is a member of the Indian Fertility Society, ESMO, and the Epidemiology Foundation of India and has participated as chairperson, faculty, and speaker at national and international conferences. She has also contributed to scientific publications and presentations in women’s health and reproductive medicine.