The Hong Kong University of Science and Technology, China
My research work mainly focuses on the construction and function of DNA nanomachines, which are cutting-edge and challenging topics. I designed and constructed unique DNA motifs using a short circular DNA nanotechnology technique and functionalized these probes with fluorophores, gold nanoparticles, small molecular drugs, and peptide ligands. To achieve plasmon resonance effects, I achieved nano-specific precision in organizing plasmonic nanoparticles on the nano DNA frameworks. My work on the DNA nanomachines provided an efficient fluorescence resonance energy transfer mechanism that realizes the bio-imaging, detection of biological events, and functions of the biomolecules. I have also been working on multilayered hybrid magnetic nanoparticles for applications in nanomedicine for the last three years.
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