ENT 2026

Recurrent otitis media, children, treatment, prevention, probiotics, pneumococcal conjugate vaccine, microbiome correction, personalized medicine.Background. Management of recurrent otitis media (ROM) in children remains challenging because of the limited and controversial efficacy of antimicrobial chemoprophylaxis, growing antibiotic resistance, and otopathogen biofilm persistence. New strategies that act on microbiome and immune predictors are therefore required to reduce recurrences and rationalise antibiotic use.Aim. To substantiate an optimised complex treatment-and-prevention algorithm for ROM in children that incorporates clinical predictors, immunological status and gut microbiome characteristics.Materials and methods. A prospective comparative-analytical study of 40 children aged 3–18 years (20 ROM; 20 ROM with comorbidities; 20 controls) is conducted with comprehensive clinical, endoscopic, audiological-tympanometric, immunological and microbiological evaluation. The comparative efficacy of complex treatment approaches, including microbiome-correcting interventions, is analysed, and patients are stratified by recurrence risk (low, medium, high) to guide differentiated management (Microsoft Excel, Statistica; p

Dr. Jamshid Karshiboev is an otorhinolaryngology (ENT) medical professional and researcher based in Tashkent, Uzbekistan. He is affiliated with the Republican Specialized Scientific and Practical Medical Center of Otorhinolaryngology and Head and Neck Diseases, a specialized institution dedicated to clinical care, scientific research, and postgraduate medical education in otorhinolaryngology and related head and neck conditions.Dr. Karshiboev is currently pursuing PhD-level doctoral research at the Center, contributing to the development of scientific knowledge and evidence-based approaches in the field of ENT medicine. His academic interests include the diagnosis, treatment, and prevention of otorhinolaryngological disorders, with a particular interest in improving clinical approaches and patient outcomes.