Prof. Vittorio Calabrese, Graduated in Medicine on 1984 at the University of Catania, after specialization in Neurology, on 1988 at University of Catania, since 1996 was Researcher at the Department of Biochemistry, School of Medicine, University of Catania. By 2001 to date Prof. Calabrese is a Professor of Clinical Biochemistry at the School of Medicine and Surgery and actual Director of School of Specialization in Clinical Pathology and Clinical Biochemistry, University of Catania and University of Messina. He is member of the Editorial Board of several high peer reviewed journals including: Journal of Neuroscience Research;  Neurochem Research;  Antioxidant Redox Signaling; Journal Neurochemistry;  Free Radical Biology Medicine; Current Neurovascular Disorders. He has been reviewer of national projects (Italian MIUR), and many foreign projects for foreign institutions. He has been member of the ASN Commission (05/E1) of the Italian MIUR for the year 2013 and 2014. He is member GEV -Area 5 - Scienze biologiche -for the year 2020-2022, as well as member AVA (ANVUR) for the year 2021-2022. His research focuses on the role of free radicals and antioxidants in human disease, particularly Alzheimer's disease and other brain disorders. His interest in identifying the most important antioxidants in the human diet and in developing novel antioxidants has critical bearing on treating human diseases and understanding how diet might cause or prevent them. Areas of his research interests includes role of Oxidative Stress and Mitochondrial dysfunction in Aging, Neurodegenerative disorders and Longevity; Proteomics and redox proteomics, Heat shock signal pathway Hormesis and Vitagenes in Neurodegeneration. The results of his researches have been reported in over 328 scientific papers published in outstanding international journals and widely cited (around 21,735 total citations), for an h Index value of 90 (ISI). He has deposited the  patents (Nr. WO 2004/07883 A1 of  10.9.2004) for the use of curcumin and its derivatives in the treatment neurodegenerative disorders; and (Nr. US20040167217) Neuroprotective effects of polyphenolic compounds.