Diabetes may be a common chronic illness that imposes right smart demands on the individual tending system. Individuals with polygenic disease have the next rate of disorder than those while not diabetes and are at multiplied risk for renal disorder, lower limb amputation and vision defect. Fleshiness may be an important risk issue for diabetes and also the prevalence of fleshiness in youngsters and adults has dramatically multiplied within the past four decades. Diabetic dyslipidemia is one among the foremost risk factors for disorder in diabetes. The characteristic options of diabetic dyslipidemia are a high plasma lipid concentration, low cholesterol concentration and multiplied concentration of tiny dense LDL-cholesterol particles. So as analysis to analyze the bioinformatics tools and methodologies accustomed in polygenic disease research, at first, this was tough to try and do as a result of it failed to have a preconceived notion concerning however the analysis would be organized and the way bioinformatics tools would be delineated or known within the analysis.